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American Health Original Papaya Enzyme Chewable 250 Tablets sodium citrate r-11c0sde{margin-top:24pxAmerican Health Original Papaya Enzyme Chewable 250 Tablets Natural Digestive Support Papain the cysteine protease enzyme found in papaya fruit is one of the few plant derived digestive enzymes that remains active across a wide pH range (approximately 3. 58. 0). This matters because most digestive enzymes are pH specific: pepsin works only in the stomach's acidic environment, while pancreatic proteases function optimally in the alkaline small